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Efficacy of auricular stimulation in the treatment of diarrhoeal irritable bowel syndrome and the mechanism of brain network modulation

Efficacy of auricular stimulation in the treatment of diarrhoeal irritable bowel syndrome and the mechanism of brain network modulation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000232
Enrollment
Unknown
Registered
2024-08-13
Start date
2024-08-15
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diarrhoeal Irritable Bowel Syndrome

Interventions

Control group:Transcutaneous non-vagus nerve stimulation, taking the "shoulder" and "wrist" auricular points for stimulation.
Treatment group:Transcutaneous auricular vagus nerve stimulation, taking "liver" and "spleen" auricular points for stimulation.

Sponsors

Institute of acupuncture and moxibustion, China Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged between 18 and 65 years of age, male or female; 2. Meeting the diagnosis of diarrhoeal irritable bowel syndrome; 3. Patients voluntarily sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1) Patients with previous organic lesions of the gastrointestinal tract such as ulcers and tumours; 2) Diseases affecting gastrointestinal tract dynamics such as thyroid and diabetes mellitus; 3) Serious systemic diseases such as heart, liver, kidney, lung and blood; 4) Patients with mental and psychological diseases and related medical history; 5) Patients with significant medical history of gastrointestinal surgery; 6) Patients who are planning to be pregnant, pregnant women and breastfeeding; 7) Patients with severe skin lesions in the auricular region and absence of the auricle.

Design outcomes

Primary

MeasureTime frame
IBS-SSS;

Secondary

MeasureTime frame
17-HAMD;Bristol Stool Form Scale;functional magnetic resonance imaging;Heart rate variability(HRV);

Countries

China

Contacts

Public ContactShaoyuan Li

Institute of acupuncture and moxibustion, China Academy of Chinese Medical Sciences

704488328@qq.com+86 159 0149 8725

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026