chronic cardiac failure
Conditions
Interventions
Control group:On the basis of conventional western medicine treatment, after 0.5h interval with western medicine, take 1 bag of Jiawei Yixin Tang granule simulator with warm water/time, orally divided
Experimental group:On the basis of conventional western medicine treatment, Jiawei Yixin Tang granules were taken with warm water 1 bag/time after 0.5h interval with Western medicine, orally divided i
Sponsors
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meet the above Western diagnostic standards and TCM syndrome differentiation standards; 2. NYHA cardiac function Grade ? and ?; 3. The primary disease was coronary heart disease and dilated cardiomyopathy. 4, aged between 65 and 80 years old; 5. Did not participate in other drug clinical studies within 1 month before inclusion; 6. Sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Heart failure after acute myocardial infarction; 2. EF > 50%; 3. Increased mortality associated with cardiogenic shock, severe ventricular arrhythmia, complete atrioventricular block, constrictive pericarditis, pericardial tamponade, pulmonary embolism, etc.; 4. Patients with severe primary diseases such as liver, kidney, hematopoietic system, abnormal kidney function, and severe mental illness; 5, uncontrolled infection, hypertension, etc.; 6. Allergy or known allergy to therapeutic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Minnesota Quality of Life in Cardiac Insufficiency Questionnaire(MLFHQ); | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum NT-proBNP, interleukin-6, tumor necrosis factor-a levels;Cardiovascular endpoint events were followed up for 12 months after the end of treatment;Hamilton Anxiety Scale(HAMA);TCM syndromes of chronic heart failure;The six-minute walk test(6-MWT);Left ventricular ejection fraction (EF), cardiac output (CO); | — |
Countries
China
Contacts
Public ContactLu Xiaohui
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Outcome results
None listed