depression
Conditions
Sponsors
The Affiliated TCM Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1) 12 years<=Age<18 years; 2) Meet DSM-5 diagnostic criteria for "depressive disorders"; 3) Meet mild (8 = 17-item Hamilton Depression Rating Scale score <14) and moderate (14 = 17-item Hamilton Depression Rating Scale score <20); 4) No suicide risk, a "no" response on all items of the Suicide Severity Rating Scale (C-SSRS), and a score of <3 on item 3 (suicide) of the HAMD-17; 5) Have not been treated with antidepressants (escitalopram, mirtazapine, etc.) and physical therapy (acupuncture, transcranial magnetic stimulation, transcranial electrical stimulation, electroconvulsive therapy, etc.) within the previous 1 month; 6) The study subjects and their guardians refused to take the medication; 7) Reads and writes properly and is able to communicate properly; 8) The study subjects and their guardians volunteered to participate in this study and signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1) Currently or previously suffered from a diagnosis consistent with other mental disorders in the DSM-5, such as bipolar disorder, schizophrenia, post-traumatic stress disorder, and personality disorders; 2) Patients with severe or unstable cardiovascular, respiratory, hepatic, renal, hematologic, or other systemic diseases, as well as patients with acute illnesses, infectious diseases, or malignant tumors, who, in the opinion of the investigator, are not suitable for enrollment in this stud; 3) Presence of a history of psychoactive substance (e.g., alcohol, drugs, etc.) abuse or dependence.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in Children's Depression Rating Scale - Revised (CDRS-R) scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| PSQI scale score difference;Difference in Children's Depression Rating Scale - Revised (CDRS-R) scores;Clinical remission rate(HAMD-17 score <7 after 8 weeks of treatment);C-SSRS scale score difference;HAMD-17 clinical reduction rate( = pre-treatment HAMD-17 score - post-treatment HAMD-17 score)/Pre-treatment HAMD-17 score;HAMA-14 scale score difference;HAMD-17 scale score difference; | — |
Countries
China
Contacts
Public ContactLin Yu
The Affiliated TCM Hospital of Guangzhou Medical University
Outcome results
None listed