Subthreshold Depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Age is 18~30 years old, gender is not limited, right-handed; 2) Meet the diagnostic criteria for subthreshold depression, that is, most of the time with two or more types of depressive symptoms, lasting for more than two weeks, accompanied by a certain degree of social function impairment, but can not meet the diagnostic criteria for depressive disorder; 3) Using the Mini International Neuropsychiatric Interview (The Mini International Neuro psychiatric Interview (MINIversion5.0)) to determine the diagnostic criteria for depression not suicidal in the Diagnostic and Statistical Manual of Mental Disorders Version 5 (Diagnostic and Statistical Manual of Mental Disorders-V, DSM-V); 4) 17-item Hamilton Depression Scale (HAMD-17) score> 7, <17; 5) Excessive thinking, suspicious and good worry, often sigh, decreased appetite, wasting, easy to fatigue, a little activity will feel tired, warm qi, irregular menstruation, loose stool, or pharyngeal discomfort such as foreign body obstruction in 2 or 2 symptoms; 6) Not receiving any depression-related treatment in the past 6 months; 7) Informed consent and voluntary participation.
Exclusion criteria
Exclusion criteria: 1) According to the DSM-V criteria, meet the diagnostic criteria of mood disorder, bipolar depression disorder, mental disorder and so on; 2) Patients with a history of previous mental illness or organic mental disorders, or depression caused by psychoactive substances and non-addictive substances; 3) Any major medical or neurological disease, a history of head trauma; 4) Endocrine disorders (such as Cushing's syndrome, Addison's disease) and other influence indicators detection; 5) Other clinical trials currently influencing the results of the study. If any of the above answers are yes, this subject could not participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tongue image;Electroencephalogram(EEG);pulse image;Functional Near-infrared Spectroscopy(fNIRS);TCM syndrome integral; | — |
Countries
China
Contacts
Beijing University of Chinese Medicine