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Observation on effect of transcutaneous electrical acupoint stimulation combined with TCM five-tone therapy in improving subthreshold depression of liver-stagnation and spleen-deficiency type

Observation on effect of transcutaneous electrical acupoint stimulation combined with TCM five-tone therapy in improving subthreshold depression of liver-stagnation and spleen-deficiency type

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000176
Enrollment
Unknown
Registered
2024-08-06
Start date
2024-03-01
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subthreshold Depression

Interventions

Control group:General mental health education.
TAES treatment group:the subjects were given general mental health education, and on this basis, the KWD-808I electronic pulse meridian therapy instrument, with density wave, frequency of 2 / 100Hz, w
Neiguan, Shenmen, Zusanli and Taichong points were selected, and electrodes were affixed respectively. Each treatment lasted for 30min, twice a week, with a total duration of 4 weeks.
TAES+TCM five-tone therapy treatment group:on the basis of the percutaneous electrical treatment using the background five tone inheritance culture co., LTD. "space field type playback equipment", cho

Sponsors

Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1) Age is 18~30 years old, gender is not limited, right-handed; 2) Meet the diagnostic criteria for subthreshold depression, that is, most of the time with two or more types of depressive symptoms, lasting for more than two weeks, accompanied by a certain degree of social function impairment, but can not meet the diagnostic criteria for depressive disorder; 3) Using the Mini International Neuropsychiatric Interview (The Mini International Neuro psychiatric Interview (MINIversion5.0)) to determine the diagnostic criteria for depression not suicidal in the Diagnostic and Statistical Manual of Mental Disorders Version 5 (Diagnostic and Statistical Manual of Mental Disorders-V, DSM-V); 4) 17-item Hamilton Depression Scale (HAMD-17) score> 7, <17; 5) Excessive thinking, suspicious and good worry, often sigh, decreased appetite, wasting, easy to fatigue, a little activity will feel tired, warm qi, irregular menstruation, loose stool, or pharyngeal discomfort such as foreign body obstruction in 2 or 2 symptoms; 6) Not receiving any depression-related treatment in the past 6 months; 7) Informed consent and voluntary participation.

Exclusion criteria

Exclusion criteria: 1) According to the DSM-V criteria, meet the diagnostic criteria of mood disorder, bipolar depression disorder, mental disorder and so on; 2) Patients with a history of previous mental illness or organic mental disorders, or depression caused by psychoactive substances and non-addictive substances; 3) Any major medical or neurological disease, a history of head trauma; 4) Endocrine disorders (such as Cushing's syndrome, Addison's disease) and other influence indicators detection; 5) Other clinical trials currently influencing the results of the study. If any of the above answers are yes, this subject could not participate.

Design outcomes

Primary

MeasureTime frame
Hamilton Depression Scale;

Secondary

MeasureTime frame
Tongue image;Electroencephalogram(EEG);pulse image;Functional Near-infrared Spectroscopy(fNIRS);TCM syndrome integral;

Countries

China

Contacts

Public ContactLIU YITIAN

Beijing University of Chinese Medicine

lytbucm@163.com+86 158 1110 1170

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026