knee osteoarthritis
Conditions
Interventions
treating group ( 1 group):a nano-enabled Lidocaine delivery acupuncture needle(Lidocaine nd-Acu)
Sponsors
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Eligibility
Sex/Gender
All
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) age from 45 to 80 years old; 2)patients meet the diagnostic criteria for knee osteoarthritis according to the 2014 National Institute for Health and Clinical Excellence criteria of the United Kingdom; 3) In recent 6 months, Kellgren and Lawrecne's radiological diagnostic criteria were in line with Grade I to Grade III; 4) The average severity of knee pain in the past week was more than 4 points (0 points representing no pain, 10 points representing extreme pain, a total of 11 scales); 5) male or female; 6) patients who signed informed consent and volunteer to participate in this project.
Exclusion criteria
Exclusion criteria: patients with a history of knee replacement surgery; 2) knee pain caused by other diseases (e.g. joint loosening, infection, malignancy, autoimmune disease, trauma, etc.). Patients with acute and chronic periarticular synovitis, bursitis, ligamentitis and other soft tissue inflammation should be evaluated by doctors to decide whether to enter the group; 3) had undergone arthroscopy or intra-articular injection within 1 year; 4) pregnant or lactating women; 5) severe acute/chronic organic or mental illness; 6) coagulation disorders (such as hemophilia); 7) participated in other clinical studies in the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster Universities Osteoarthritis index,WOMAC score;Venous blood plasma inflammatory factor IL-1/IL-6/TNF-a; | — |
Secondary
| Measure | Time frame |
|---|---|
| LKSS score;TCM symptom scale score;Knee joint ultrasonography; | — |
Countries
China
Contacts
Public ContactWang Peng
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Outcome results
None listed