subthreshold depression
Conditions
Interventions
Tai Chi combined with rTMS group:Tai Chi + rTMS stimulation
Tai Chi combined with sham rTMS group:Tai Chi + sham rTMS stimulation
Sponsors
The Third People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
19 Years to 30 Years
Inclusion criteria
Inclusion criteria: 1) Age 19 to 30 years old, gender is not limited; 2) The Center for Epidemiologic Studies Depression Scale (CES-D) score between 16 and 25; 3) Right-handedness; 4) Informed consent and voluntary participation.
Exclusion criteria
Exclusion criteria: 1) Satisfaction of diagnostic criteria for mood disorders, bipolar depressive disorder, psychosis, etc. according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) diagnostic criteria; 2) Previous history of major depression, epilepsy or family history of epilepsy, neurodegenerative disease, cerebrovascular disease, neurological disease, history of brain injury, etc; 3) Prior use of psychiatric medications or addiction disorders (e.g., drug abuse, alcoholism, etc.); 4) Presence of metal implants in the body, such as pacemakers, cochlear implants, metal joints, and other ferromagnetic foreign objects, high fever, pregnancy, claustrophobia, and other contraindications to MRI scanning; 5) Patients with severe sleep disorders or severe anxiety disorders. The insomnia severity index (ISI) =22, Hamilton Anxiety Scale (HAMA) score =29; 6) Those who are participating in other clinical trials that affect the evaluation of the results of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient Health Questionnaire, PHQ-9; | — |
Secondary
| Measure | Time frame |
|---|---|
| Perceived Stress Scale, PSS;Medical Outcomes Study 36-Item Short-Form Health Survey,SF-36;Hamilton Depression Scale,HAMD;Generalized Anxiety Disorder,GAD-7;Snaith-Hamilton pleasure scale, SHAPS;Magnetic Resonance Image;Chinese Affective Scale, CAS;Pittsburgh Sleep Quality Index,PSQI; | — |
Countries
China
Contacts
Public ContactJingsong Wu
Fujian University of Traditional Chinese Medicine
Outcome results
None listed