migraine
Conditions
Interventions
Non meridian acupoint embedding group:Non meridian acupoint embedding
Placebo napex acupoint catgut embedding therapy group :Placebo napex acupoint catgut embedding therapy
Napex acupoint catgut embedding therapy group:Napex acupoint catgut embedding therapy
Healthy control group:None
Placebo non meridian acupoint embedding group:Placebo non meridian acupoint embedding
Sponsors
Nanjing Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Meet the diagnostic criteria of migraine without aura; 2) Patients aged between 18 and 65 years old, with a course of more than 6 months and an average of more than 2 headache episodes per month; 3) No migraine preventive treatment including acupuncture and drugs in the past 1 month; 4) Not taking psychoactive or vasoactive drugs in the last 3 months; 5) No long-term habit of taking analgesic drugs; 6) Patients voluntarily receive preventive treatment and sign informed consent forms.
Exclusion criteria
Exclusion criteria: 1) The type of headache other than migraine without aura was consistent with ICHD-3; 2) There are organic lesions such as tumors, inflammation, degenerative diseases, etc. 3) Combined with severe neurological, cardiovascular, digestive, urinary, hematological, endocrine system diseases unrelated to migraine; 4) Pregnant and lactating women; 5) Have a serious mental disorder or cognitive impairment that prevents them from communicating properly and receiving medical treatment; 6) Suspected or confirmed history of alcohol or drug abuse. 7) Have contraindications to MRI examination such as metal implants in the body and claustrophobia; 8) Have severe asymmetric head anatomical structure or clear lesions found in MRI examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| frequency of headache attacks;the number of headache attack days; | — |
Secondary
| Measure | Time frame |
|---|---|
| headache severity;amplitude of low frequency fluctuation,ALFF;Migraine specific Quality of Life questionnaire;the improved response rate by 50%; | — |
Countries
China
Contacts
Public ContactRenzhong Kou
Nanjing Hospital of Traditional Chinese Medicine
Outcome results
None listed