Nicotine dependence
Conditions
Interventions
auricular electroacupuncture group :auricular electroacupuncture
Healthy non-smokers:No intervention (provide baseline fMRI data)
Sponsors
Shaanxi University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria of smokers 1). Adult smokers who are willing to quit smoking, aged between 18 and 35 years old. 2) . Smokers with moderate or severe nicotine dependence, and FTCD=4. 3). Speak clearly and willing to finish MRI and EEG examination. 4). Willing to participate and provide signed informed consent. 5).Conforms to the diagnostic criteria of DSM-v. 6) Smokers who had not quit smoking within 3 months. 7). There were no contraindications to MRI scaning. Note: smokers satisfy the above seven items at the same time will be included in this study. 2. Inclusion criteria of healthy non-smokers 1) No addiction history, no smoking or has smoked no more than 5 cigarettes in lifetime. 2) Aged between 18 and 35 years old, and the age and sex were matched with smoking participants. 3) Willing to participate and provide signed informed consent, and there were no contraindications to MRI scaning. Note:non- smokers satisfy the above 3 items at the same time will be included in this study.
Exclusion criteria
Exclusion criteria: 1. Exclusion critria of smoking participants 1). Smokers have a history of organic brain disease or craniocerebral injury history, coma. 2). Pregnant and lactating women 3). Smokers who have received pharmacological, psychobehavioral therapies or acupuncture for smoking cessation in last 3 months. 4). Patients who met DSM-5 diagnostic criteria for mental disorders within 3 generations, or long-term use of psychotropic drugs. 2. Exclusion criteria of non-smokers 1) Had a history of organic brain disease or craniocerebral injury and coma. 2) Pregnant and lactating women 3) Patients who met DSM-5 diagnostic criteria for mental disorders within 3 generations, or long-term use of psychotropic drugs 4) Nuclear magnetic resonance (NMR), electrical check contraindication Notes: participants who meet the one of obove items will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fMRI;QSU-Brief;Abstinence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| MNWS;Replase rate;Smoking cravings;Adverse events;PSQI;EEG;FTCD;SDS; | — |
Countries
China
Contacts
Public ContactZhang Yingying
Shaanxi University of Traditional Chinese Medicine
Outcome results
None listed