perioperative neurocognitive impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 60= age =85 years; Internal fixation for hip fracture: total (half) artificial hip replacement/closed reduction intramedullary nailing internal fixation; According to the American Society of Anesthesiologists grading standards ASA II to III; The patient has a certain level of education, and the cumulative time of education is =1 year; The estimated operation time is more than 30 minutes. Patients participate voluntarily and sign informed consent
Exclusion criteria
Exclusion criteria: Rule out serious organic diseases; Patients who did not undergo skull repair after craniotomy; Have severe speech impairment, severe vision or hearing impairment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MMSE;TICS-m;CAM-CR; | — |
Secondary
| Measure | Time frame |
|---|---|
| Brain injury-associated proteins;Inflammatory factor; | — |
Countries
China
Contacts
People'S Hospital Affiliated to Fujian Chinese Traditional Medicine University