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Clinical Trial Protocol for Investigating Biological Characteristics of Different Syndromes in Heart Failure with Preserved Ejection Fraction (HFpEF) Based on Proteomics and Metabolomics Studies

Proteomics and metabolomics-based study of the biological characteristics of different TCM syndromes of heart failure with preserved ejection fraction (HFpEF)

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2024000120
Enrollment
Unknown
Registered
2024-07-07
Start date
2023-11-09
Completion date
Unknown
Last updated
2024-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hearth failure

Interventions

control group:none

Sponsors

Xi Yuan Hospital, China Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 95 Years

Inclusion criteria

Inclusion criteria: Those who met the western medical diagnostic criteria for HFpEF; those who had a cardiac function (NYHA) classification standard of class II-IV; those who were 45-95 years old and of any gender; and those who gave consent from the patients or their families and signed the informed consent form.

Exclusion criteria

Exclusion criteria: Heart failure due to congenital heart disease, valvular heart disease, myocarditis, autoimmune disease, etc.; those with co-morbid malignant tumours; patients who refused to sign the informed consent form, and those with mental abnormality; women in pregnancy or breastfeeding; and those who have participated in other studies in the last 3 months.

Design outcomes

Primary

MeasureTime frame
proteomics;LVEF;HbA1c;E/e';NT-pro BNP;metabolomics;EAT;

Countries

China

Contacts

Public ContactLiu Jian gang

Xi Yuan Hospital, China Academy of Chinese Medical Sciences, National Center for Clinical Cardiovascular Disease of Traditional Chinese Medicine, Beijing 100091

liujiangang2002@sina.com13651208096

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026