Gastrointestinal dysfunction after esophageal cancer surgery
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Naval Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: The study will include male or female patients of age 18–60 years; those diagnosed as having EC and will be undergoing elective surgery; those with American Society of Anesthesiologists (ASA) classification I–III [33]; those without any previous history of thoracic or abdominal surgery; and those who have signed informed consent.
Exclusion criteria
Exclusion criteria: The study will exclude patients who had received epidural anesthesia, need to undergo other synchronized operations, had received drugs that affect the intestinal function within 1 month before the study, have intraoperative and postoperative complications and require long-term intensive care (more than 24 h), have mental disorder or a history of opioid abuse, (6) had received acupuncture treatment within 1 month before the study, had participated in other clinical studies 3 months before enrolling for this study, have severe hepatic and renal dysfunction, had undergone emergency reoperations, and have second- or third-degree heart blocks and tachyarrhythmias with a baseline heart rate of <50 beats/min or have electrical stimulation devices (pacemakers or implantable defibrillators); those who experience gastrointestinal bleeding before operation (bleeding volume: 800 mL); and those with ASA classification IV or V (IV indicates that the patient has a severe systemic disease that poses an ongoing threat to life; V indicates that the patient is dying and is expected not to survive without surgery).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the time of first defecation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tolerance time for semiliquid and solid foods;Time of first exhaust;Postoperative hospitalization;EQ -5D-5L scoring;Postoperative quality of life;Hospital Anxiety and Depression Scale;I-FEED scoring system;Time of first ambulation;Laboratory test indicators (blood routine, CRP, L-6, IL-10, TNF-a);Demand for postoperative analgesics and defecation medication; | — |
Countries
China
Contacts
Public ContactXiaofeng Zhai
The First Affiliated Hospital of Naval Medical University
Outcome results
None listed