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A risk-predictive model of gastric "inflammation-cancer" transformation based on the combination of disease and syndrome: a perspective study protocol

A risk-predictive model of gastric "inflammation-cancer" transformation based on the combination of disease and syndrome: a perspective study protocol

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2024000089
Enrollment
Unknown
Registered
2024-06-04
Start date
2021-01-01
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer, Precancerous Lesions of Gastric Cancer

Interventions

CNAG group:None
CAG group:None
GAC group:None
PLGC group:None

Sponsors

Hainan Hospital, Guangdong Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. =35 years old; gender is not limited. 2. The diagnosis of chronic non-atrophic gastritis (CSG), chronic atrophic gastritis (CAG), precancerous lesions of gastric cancer (PLGC), and gastric adenocarcinoma (GC) is established through gastroscopy and examination of gastric mucosal pathology and histology. 3. It is possible to have effective communication. 4. Informed consent, voluntary participation.

Exclusion criteria

Exclusion criteria: 1. Received drug treatment research within the past month. 2. The combination of autoimmune gastritis (Type A chronic atrophic gastritis), peptic ulcers (Stage A1-H2), gastroesophageal reflux disease, gastric polyps, hypertrophic gastritis, and ulcerative colitis. 3. Individuals with gastric cancer other than gastric adenocarcinoma include those with gastric signet ring cell carcinoma (SRCC), gastric cardia cancer (GCC), gastric mucinous cell carcinoma, etc. 4. Patients with malignant tumors who have undergone surgery, radiation therapy, or chemotherapy within the last 5 years. 5. Combination of severe organic illnesses, including cardiac conditions (NYHA class III-IV heart failure, hemodynamically unstable myocardial infarction, etc.), liver problems (cirrhosis, etc.), renal problems (chronic kidney failure, uremia, etc.), renal problems (chronic kidney failure, uremia, etc.), pulmonary diseases (tuberculosis, acute asthma attack, lung infection, etc.), and autoimmune disorders (systemic lupus erythematosus, etc.). 6. Allergies or multiple drug sensitivities. 7. People with concurrent serious mental disorders who are unable to participate in the study due to conditions such as schizophrenia, depression, anxiety, and dementia. 8. Existing pregnancy or breastfeeding. 9. Non-cooperative survey participants.

Design outcomes

Primary

MeasureTime frame
TCM syndrome information;Key molecular markers (LYZ, SST);Gastroscope Report;Pathological Report;Serological markers;

Secondary

MeasureTime frame
Prognostic information;Epidemiological information;

Countries

China

Contacts

Public ContactJinglin Pan

Hainan Hospital, Guangdong Provincial Hospital of Traditional Chinese Medicine

panjinglinlove@126.com18818840586

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026