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Clinical efficacy of electroacupuncture at acupoints below elbow-hand shaoyin/Jueyin meridian on improving chronic heart failure (acute exacerbation) -- A multicenter, randomized and controlled trial

Clinical efficacy of electroacupuncture at acupoints below elbow-hand shaoyin/Jueyin meridian on improving chronic heart failure (acute exacerbation) -- A multicenter, randomized and controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000082
Enrollment
Unknown
Registered
2024-05-27
Start date
2024-05-30
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic heart failure

Interventions

Acupuncture group:Guided by guidelines, standardized Western medicine treatment combined with electroacupuncture treatment
Control group :standardize Western medicine treatment under the guidance of guidelines

Sponsors

Department of Cardiovascular Medicine, First Affiliated Hospital of Anhui University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 79 Years

Inclusion criteria

Inclusion criteria: 1. The age is 30~79 years old, regardless of gender. 2. Meet the diagnostic criteria of chronic heart failure: 1)LVEF=50% (improved Simpson method); 2) Have a history of heart disease; 3) With or without symptoms/signs of heart failure such as dyspnea, fatigue and fluid retention (edema). 3 suffering from a history of heart failure or clinical symptoms of heart failure for more than 3 months. 4. Acute exacerbation criteria of chronic heart failure 1) Symptoms: Patients with stable cardiac function have unexplained fatigue or significantly reduced exercise endurance; Difficulty in breathing due to exertion, paroxysmal dyspnea at night, and the need to raise the head with a pillow when sleeping; Sudden severe dyspnea, sitting breathing, wheezing, irritability and fear. 2) Signs: Left ventricle was found to be larger than before; The basal heart rate is 15-20 beats/min faster than before; Smell the law of running horses; There are wet rales, dry and wet rales and wheezing sounds in both lungs, especially at the bottom of the lungs. The above situation has changed dynamically. Acute exacerbation is considered if you have any of the above items. 5. Nyha cardiac function grade III and above; 6. BNP = 100 pg/ml or NT-probnp = 300 pg/ml; 7. Percutaneous acupoint electrical stimulation can be accepted; 8. Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. The first acute heart failure. 2. One of the following diseases: ? within 30 days of acute coronary syndrome; ? within 6 months of revascularization; ? Hypertension (systolic blood pressure =180mmHg and/or diastolic blood pressure = 110mmhg) which is difficult to control with drugs; (4) uncontrollable malignant arrhythmia caused by sinus or atrioventricular block with degree ? or above without pacemaker; ? Pericardial tamponade; ? Active pericarditis; ? myocarditis; 8 pulmonary embolism; Pet-name ruby serious valve disease; Attending cor pulmonale; ?11 Stroke patients in recent 6 months, etc. 3. Cardiac resynchronization therapy. 4. Intravenous use of diuretic, cardiotonic and vasodilator drugs in the past 3 days. 5. alanine aminotransferase > 2 times the upper limit of normal ULN (upper limit of normal value). 6. serum creatinine > 265 umol/l. . 7. Patients with severe endocrine diseases such as hyperthyroidism. 8. Hemoglobin =9g/dl. 9. Mental patients. 10. Patients with malignant tumors. 11. Pregnant or planned pregnant women, lactating women. 12. Those with bleeding tendency, allergic skin or infectious skin diseases. 13. Participate in other researchers in the last two months. 14. Those who are unable to carry out the 6-minute walking test due to physical impairment or other reasons.

Design outcomes

Primary

MeasureTime frame
Minnesota quality of life scale score;

Secondary

MeasureTime frame
Holter monitoring electrocardiogram;the integral of TCM syndrome;6-minute walking distance;NYHA classification of cardiac function;Cardiac Echocardiography Parameters;NT-proBNP;

Countries

China

Contacts

Public ContactWang Shiguang

First Affiliated Hospital of Anhui University of Traditional Chinese Medicine

dr_shguang@ahtcm.edu.cn+86 138 5695 8093

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026