Early onset Parkinson's disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Meet the diagnostic criteria for Parkinson's disease; 2. Age 25-49 years; 3. Hoehn-Yahr stage 1-4; 4. Clear consciousness, stable vital signs, and able to communicate normally; 5. Willing to sign an informed consent form.
Exclusion criteria
Exclusion criteria: Patients will be excluded if they meet any of the following aspects: 1.Parkinsonism syndrome and Parkinson plus syndrome caused by cerebrovascular disease, poisoning and other causes; 2. Presence of serious diseases such as severe liver or kidney disease, blood disorders, tumors, endocrine diseases, or pain; 3. Concurrent participation in other drug and acupuncture clinical trials; 4. Communication barriers such as mental illness, hearing impairment, or cognitive impairment; 5. History of alcohol abuse or drug abuse; 6. Contraindications to acupuncture, such as ableeding tendency or local infection at acupoints; 7.Pregnant or planning to become pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Unified Parkinson's Disease Rating Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proton magnetic resonance spectroscopy;Parkinson's Disease Daily Quality of Life-39 ;diffusion tensor imaging;Resting-state functional magnetic resonance imaging;Parkinson's disease non-motor Symptom Assessment Scale;Synapsys human posture balance system;musculoskeletal ultrasound;3D gait analysis; | — |
Countries
China
Contacts
State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Affiliated Hospital of Guangzhou University of Chinese Medicine