coronary heart disease,coronary calcification
Conditions
Interventions
Group 1:DLTM Formula
Group 2:placebo
Sponsors
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Patients definitively diagnosed with coronary heart disease or confirmed by coronary angiography or coronary CT to have coronary artery stenosis =50%, and meet the criteria for stable coronary artery disease; 2) Age between 18 to 75 years, gender unrestricted; 3) Have undergone a 64-slice coronary CT angiography (CTA) within the last 3 months, with the results showing a coronary calcification score between 100 and 2000; 4) Patients voluntarily participate in this trial and sign a written informed consent form.
Exclusion criteria
Exclusion criteria: 1) Patients with other serious cardiac diseases or acute cerebrovascular diseases; 2) Patients with acute or chronic infections, liver or kidney dysfunction, coagulation disorders, thyroid dysfunction, and other severe primary diseases of the immune or hematopoietic systems; 3) Patients with psychiatric diseases or severe neuroses; 4) Participation in another clinical trial within the last month; 5) Patients who have previously undergone coronary artery interventional procedures for calcification; 6) Individuals with allergic constitutions, allergies to known components of the trial medication, or iodine allergies. 7) Pregnant women, those attempting to conceive, or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| coronary artery calcification volume score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiac function indicators, cardiac metabolic risk factors, inflammation-related laboratory indicators, mineral metabolism laboratory indicators, and other hematological indicators;Seattle Angina Questionnaire (SAQ) score;Traditional Chinese Medicine syndrome improvement score/blood stasis syndrome score;Changes in coronary plaque burden;coronary artery Agatston score;Vascular stiffness change; | — |
Countries
China
Contacts
Public ContactYue Liu
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed