Hyperuricaemia
Conditions
Interventions
treatment group:Yinling Qushi granule
control group:Yinling Qushi granule simulator
Sponsors
Guangdong Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: People aged between 18 and 75 years (including 18 and 75 years) Diagnosis of hyperuricemia Diagnosis of dampness syndrome Informed consent is signed by participants.
Exclusion criteria
Exclusion criteria: 1.People with secondary hyperuricemia, such as hyperuricemia secondary to malignant tumors, blood diseases, kidney diseases, chronic poisoning, etc; 2.People who have a history of alcoholism and have not abstained in the last 3 months 3.one or more previous episodes of gouty arthritis; 4.In the past 4 weeks, the subjects have taken uric acid lowering drugs, or drugs that can cause increased blood uric acid(1) Antituberculosis drugs: pyrazinamide/ethambutol/isoniazid, (2) low-dose aspirin, (4) loop diuretics and thiazide diuretics and antihypertensive drugs containing diuretics, (5) niacin, (6) high-dose vitamin C, (7) tumor chemotherapeutics, (8) cyclosporine; 5.Pregnancy and lactation, or the possibility of pregnancy and failed to take effective contraceptive measures; 6.Glutamic pyruvic transaminase or glutamic oxalacetic transaminase or creatinine is 2 times or more than the normal value; 7.Subjects with severe organic diseases, mental disorders or other reasons can not cooperate with treatment; 8.Allergic or ineffective to the test drug ingredient.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Score of dampness syndrome;Blood uric acid drop number; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of hyperlipidemia;Cardiovascular event incidence;Joint ultrasound;hsCRP;TNF-a;Incidence of hyperlipidemia;IL-6;Incidence of gout;Urinary beta-2 microglobulin;glomerular filtration rate;Blood and urine metabolites;Incidence of diabetes;coating on the tongue;Fecal flora; | — |
Countries
China
Contacts
Public ContactXiaohong He
Guangdong Hospital of Traditional Chinese Medicine
Outcome results
None listed