atopic dermatitis
Conditions
Interventions
2:dupilumab and Western conventional treatment
1:Traditional Chinese medicine combined with dupilumab and Western conventional treatment
Sponsors
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
6 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) meet the diagnostic criteria of Hanifin and Rajka. (2) No sex limit, age 6-65 years old (3) patients with moderate and severe atopic dermatitis, eczema area and severity index (EASI) = 7 or IGA score = 3 (4) the patient himself or his agent agrees to be treated with dupilumab. (5) patients whose blood system, liver, kidney, heart and other systems are basically normal. (6) patients with good compliance, who can be injected with dupilumab at a specified time and fill in the data such as the scale regularly.
Exclusion criteria
Exclusion criteria: (1) patients with other skin diseases such as scabies, psoriasis, seborrheic dermatitis that affect the judgment of skin lesions. (2) patients suffering from mental diseases, malignant tumors, diabetes and heart disease, pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| median recurrence time;relapse rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| i-VAS(insomnia visual analog scale);IGA(inventor global assessment);p-VAS(pruritus visual analog scale);DLQI(dermatology life quality index);EASI(eczema area and severity index);POEM(patient oriented eczema measure);SCORAD(scoring for Atopic Dermatitis ); | — |
Countries
China
Contacts
Public ContactMo Xiumei
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed