Sepsis-related Chronic Care Illnesses
Conditions
Interventions
Control Group:Continuous pumping of enteral nutrition solution.
Huanglian Decoction Control Group:" Day 3 Night 2 " method was given enteral nutrition solution.Nasal feeding was not given at other time points. Huanglian Decoction was given at regular time.
Observation Group:"Day 3 Night 2" method of administration of enteral nutritional solution. Nasal gavage was not given at other time points.
Huanglian Decoction Group:Enteral nutrient solution was given by the method of"Day 3 Night 2".Huanglian Decoction was given at the same time as the enteral nutrient solution. Nasogastric feeds were no
Sponsors
Jiangsu Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria 1) Those who met the diagnostic criteria of sepsis-related CCI. 2) Age between 18 and 85 years old, gender is not limited. 3) Receive enteral nutrition therapy. 4)No serious metabolic disease and other diseases of the digestive tract, such as radiation enteritis and broken bowel syndrome. 5) Informed consent and volunteer to be tested.
Exclusion criteria
Exclusion criteria: Exclusion Criteria 1) ICU stay less than 14 days. 2) Mechanical intestinal obstruction, gastrointestinal hemorrhage. 3) Refusal or inability to perform enteral nutrition therapy. 4) Frequent death or failure of resuscitation, inability to cooperate or refusal to complete the relevant examination. 5) Pregnant and lactating women. 6) Patients who are participating in clinical trials of other drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thickness of the median femoral, rectus femoris, and tibialis anterior muscles measured by ultrasound, and cross-sectional area of the rectus femoris muscle;Diaphragmatic indicators (thickness, rate of change, mobility) measured by ultrasound;Ultrasound-measured intra-abdominal fat thickness, including subcutaneous and visceral fat thicknesses; | — |
Secondary
| Measure | Time frame |
|---|---|
| 28- and 90-day survival rates;NRS2002 score;Serum nutritional indicators: haemoglobin, albumin, prealbumin and testosterone;APACHE II score;SOFA score;NUTRIC score; | — |
Countries
China
Contacts
Public ContactJiang hua
Jiangsu Provincial Hospital of Chinese Medicine
Outcome results
None listed