Osteoporosis
Conditions
Interventions
Treatment:Calcium+Vitamin D+Alendronate Sodium+Yigu Decoction
Control group:Calcium+Vitamin D+Alendronate Sodiumg
Sponsors
The Third Affiliated Hospital of Zhejiang Chinese Medical University
Eligibility
Sex/Gender
All
Age
55 Years to 95 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria and age standards of this project (2) Inclusion criteria include those who have not taken anti osteoporosis drugs or other treatments within 3 months; (3) Patients willing to take traditional Chinese medicine decoction for treatment; (4) Meets normal height/body mass index, physical activity scale (PAS) = 180 points, and has no bad habits; (5) Sign the informed consent form for clinical research.
Exclusion criteria
Exclusion criteria: (1) Patients with non primary osteoporosis: 1) endocrine cortisol, hyperthyroidism, primary hyperparathyroidism, acromegaly, hypogonadism, diabetes, etc. 2) Nutritional protein deficiency, vitamin C deficiency, low calcium diet, alcoholism, etc 3) Chromosomal abnormalities in hereditary osteogenesis imperfecta. 4) Liver disease. 5) Hemodialysis for chronic nephritis caused by kidney disease. 6) Medications such as corticosteroids, antiepileptic drugs, anti-tumor drugs (such as methotrexate), heparin, etc Sporadic systemic osteoporosis can be seen in long-term bed rest, paraplegia, space flight, etc; Localized bone atrophy can be seen after fractures, Sudecks bone atrophy, and post injury bone atrophy Gastrectomy for gastrointestinal malabsorption Rheumatoid arthritis Multiple myeloma metastasis, monocytic leukemia, Mast Cell disease, etc Other causes include bone loss, transient or migratory osteoporosis. (2) Patients with incomplete original data records; (3) Patients with severe chronic primary diseases such as cardiovascular, cerebrovascular, liver, kidney, respiratory, and hematopoietic systems, as well as mental illness; (4) Those who have used traditional Chinese medicine to treat osteoporosis in the past month; (5) Patients with combined fresh fractures and severe multiple fractures;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone mineral density; | — |
Secondary
| Measure | Time frame |
|---|---|
| Traditional Chinese Medicine Syndrome Score;miRNA; | — |
Countries
China
Contacts
Public ContactChen Zhineng
The Third Affiliated Hospital of Zhejiang Chinese Medical University
Outcome results
None listed