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Clinical Observation of Patients with Diarrhea-predominant Irritable Bowel Syndrome Treated by Xifeng Huashi Prescription Combined with Low FODMAP Diet

Clinical Observation of Patients with Diarrhea-predominant Irritable Bowel Syndrome Treated by Xifeng Huashi Prescription Combined with Low FODMAP Diet

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2024000041
Enrollment
Unknown
Registered
2024-04-02
Start date
2023-03-29
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diarrhea irritable bowel syndrome

Interventions

low FODMAP diet group:Strictly follow the low-FODMAP diet for 4 weeks.
Placebo group:Placebo granules, 2 bags twice a day, take them with boiled water for 4 weeks, and continue to eat as usual.
Xifeng Huashi Prescription:The traditional Chinese medicine compound Xifeng Huashi granule was taken twice a day with 2 bags of boiled water for 4 weeks,and continue to eat as usual.
Xifeng Huashi Prescription + low FODMAP diet group:The traditional Chinese medicine compound Xifeng Huashi granule was taken twice a day with 2 bags of boiled water for 4 weeks in strict accordance wi

Sponsors

Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. meet the diagnostic criteria of western medicine of IBS-D. 2. meet the diagnostic criteria of TCM syndrome of liver depression and spleen deficiency. 3. 18-70 years old (including 18 years old and 70 years old), regardless of gender. 4. informed consent and voluntary subjects. The process of obtaining informed consent should be in accordance with ethical principles.

Exclusion criteria

Exclusion criteria: 1.patients with gastrointestinal organic diseases. 2.patients with severe heart, liver, kidney, respiratory, blood and endocrine diseases. 3.Psychiatric patients and severe neurosis patients. 4.Women who are pregnant, lactating or have a pregnancy plan. 5.vegetarians or lactose intolerant, severely partial eaters, or those who cannot accept the low FODMAP diets prescribed in this study because of religious beliefs. 6.patients with poor compliance with doctor's orders and allergic to this drug. 7.patients who are participating in other clinical studies.

Design outcomes

Primary

MeasureTime frame
Diamine oxidase activity;Blood endotoxin;D-Lactic acid;

Countries

China

Contacts

Public ContactHui Li

Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine

xuxiangxiangx2021@163.com+86 176 0155 8686

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026