Skip to content

Discussion on the prevention of recurrence and inflammatory gland transformation after surgery for colorectal adenomas with modified Shenling Baizhu powder based on the theory of spleen deficiency dampness and blood stasis, and the influence on the biological characteristics of intestinal flora.

Internal Medicine in Traditional Chinese Medicine

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000039
Enrollment
Unknown
Registered
2024-03-31
Start date
2024-04-01
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal adenoma

Interventions

Observation group: modified Shenling Baizhu powder
Control group:none

Sponsors

The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Colorectal polyps found by colonoscopy and endoscopic polypectomy were performed, which met the diagnostic criteria for colorectal adenoma after surgery; (2) Meet the diagnostic criteria for spleen deficiency and dampness stasis syndrome in traditional Chinese medicine; (3) Age between 18-70 years old, gender is not limited; (4) Not taking relevant drugs that may prevent the effects of drugs, such as aspirin, celecoxib, folic acid tablets, berberine, etc.; (5) Patient informed consent and signed consent form;

Exclusion criteria

Exclusion criteria: (1) There are serious complications, such as intestinal root obstruction, gastrointestinal bleeding, etc.; (2) Those who have been pathologically confirmed to have cancer (3) Combined with other such as serrated polyps, juvenile polyposis syndrome, familial adenomatous polyposis, etc.; (4) Those who suffer from mental disorders and are unable to cooperate with clinical diagnosis and treatment; (5) Pregnant women or lactating women; (6) Patients with other serious primary diseases, such as liver, kidney, cardiopulmonary organ damage; (7) Those with allergies or a history of allergies to multiple drugs

Design outcomes

Primary

MeasureTime frame
TCM symptom score evaluation;Biological characteristics of the gut microbiota;Pathological examination;Tumor Necrosis Factor alpha (TNF-a);Colonoscopy;Interleukin-8(IL-8);Interleukin-6 (IL-6);

Secondary

MeasureTime frame
Evaluation of recurrence;

Countries

People's Republic of China

Contacts

Public ContactWang Jin cheng

The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine

1054608254@qq.com13074973828

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026