severe acute pancreatitis
Conditions
Interventions
control group:Basic treatment +Indwelling nasojejacual nutrition tube
experimental group:Basic treatment + Nasal feeding of Gansui through a nasojejacual nutrition tube
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Meets the diagnostic criteria for "moderate severe acute pancreatitis" or "severe acute pancreatitis" (refer to the 2021 edition of Chinese Guidelines for Diagnosis and Treatment of Acute Pancreatitis); (2) Gansui can be administered through a nasojejacual nutrition tube; (3) Voluntarily participate in this study and sign an informed consent form; (4) Age = 18 and = 75 years old, regardless of gender.
Exclusion criteria
Exclusion criteria: (1) No gastrointestinal administration route; (2) Have a history of major digestive surgery in the past; (3) Patients who are currently participating in or have participated in other clinical trials within the month prior to this study; (4) Allergic reactions to therapeutic drugs; (5) Patients with fertility requirements or those who are pregnant or breastfeeding; (6) Liver function: Child Pugh C-grade; (7) Kidney function: CKD stage 4 or 5.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intra-abdominal pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Abdominal perfusion pressure;Hospitalization expenses;lipase;CT severity index score;arterial oxygenation index, CO2 partial pressure;ICU hospitalization days;amylase;Incidence of complications;Hospitalization days;C-reactive protein;Procalcitonin;abdominal circumference;APACHE II score;White blood cell count, percentage of neutrophils;Ventilator parameters (mean airway pressure, airway resistance);Gastrointestinal motility score; | — |
Countries
China
Contacts
Public Contactzhantao shen
Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed