Cerebrovascular disease
Conditions
Interventions
Angong Niuhuang Pill group:Angong Niuhuang Pill
Control group:Placebo
Sponsors
Affiliated Hangzhou First People's Hospital, Xihu University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1.Being 18 years of age or older; 2.Having experienced an acute ischemic stroke; 3.Being within 24 hours of stroke onset or last-seen well; 4.Having a National Institutes of Health Stroke Scale (NIHSS) score of at least 6 before entering the trial; 5.Undergoing multimodal imaging assessment where CT artery (CTA) confirmed that the stroke was caused by occlusion of a large vessel in the anterior circulation; 6.The patients or their legal representatives providing signed informed consent.
Exclusion criteria
Exclusion criteria: 1.NCCT suggests intracranial hemorrhage; 2.Active bleeding or a significant bleeding tendency; 3.Patients with renal failure, serum creatinine =264umol/L; 4.pre-existing mRS=2; 5.previous allergy to contrast media; Allergic to known ingredients of Angong Niuhuang pills; 6.Multiple organ failure, can not tolerate surgery 7.The expected survival time of other diseases (such as malignant tumors) is less than 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| modified Rankin Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Great functional outcomes;Recovery of neurological impairment;Early neurological improvement rate; | — |
Countries
China
Contacts
Public ContactCongguo Yin
Department of Neurology, Affiliated Hangzhou First People's Hospital, Xihu University School of Medicine
Outcome results
None listed