Effect of an herbal gel for the prevention of acute radiation dermatitis in patients with cancer: an open-label randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

ITMCTR

Registry ID

ITMCTR2024000016

Enrollment

Unknown

Registered

2024-01-30

Start date

2020-11-23

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

radiation dermatitis

Interventions

interventional group:gel treatment upon the development of grade 2 RID

prophylactic group:gel treatment one day before RT

Eligibility

Sex/Gender

All

Age

32 Years to 86 Years

Inclusion criteria

Inclusion criteria: The eligible patients were aged =18 years with pathologically confirmed breast, lung, or head and neck cancer of any stage, and scheduled to receive RT for =4 weeks.

Exclusion criteria

Exclusion criteria: The exclusion criteria were prior RT or serious lesions on the skin in the treatment area, poor Eastern Cooperative Oncology Group (ECOG) performance status score (>2), pregnancy or lactation, severe or uncontrolled systemic disease or infection, known allergy or hypersensitivity to gels, significant psychiatric disturbance, drug addiction, or alcohol dependence.

Design outcomes

Primary

Measure	Time frame
acute radiation dermatitis;	—

Secondary

Measure	Time frame
symptom burden;Eastern Cooperative Oncology Group performance status score;numerical rating scale;Health-related quality of life;	—

Countries

China

Contacts

Public ContactJie Liu

Guang'anmen Hospital, China Academy of Chinese Medical Sciences

dr.liujie@163.com13718716339

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026