Otitis Media with Effusion
Conditions
Interventions
Experimental group:The combination of traditional Chinese medicine with western medicine therapy
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Adult refractory secretory otitis media patients, as follows: (1) Age 18-70 years old; (2) Patients diagnosed with OME through otoscopy, pure tone audiometry, and acoustic immittance examination, and their medical history was less than 3 months; (3) Eustachian tube pressure measurement score (TMM score) 0-1 score; (4) refusal of invasive treatment, and TCM syndrome differentiation for spleen deficiency and dampness syndrome; (5) Informed consent, can cooperate with treatment and follow-up, and sign informed consent
Exclusion criteria
Exclusion criteria: (1) fluctuating sensorineural deafness; (2) Otoscopy examination of tympanic membrane and promontory adhesion or external otitis (external ear canal exudation, fungal infection, etc.); (3) Abnormal opening of eustachian tube is clearly found; (4) Eligible for surgical treatment due to other nasal, sinus or ear diseases; (5) A history of middle ear, nasal cavity and nasopharyngeal surgery on the affected side; (6) A history of cleft palate or other malformations or related surgical repair; (7) A history of head or neck surgery or radiotherapy; (8) Patients with ciliary immobility syndrome; (9) The expected survival of malignant tumors was less than 12 months; (10) The investigator believes that the patient has other conditions that are not suitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical response rate after 8 weeks of treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| A-B gap;ETDQ-7 score;Valsalva action;Clinical response rate after 2 weeks of treatment;Clinical response rate after 4 weeks of treatment;TMM score; | — |
Countries
China
Contacts
Public ContactZhong Zhen
Peking University First Hospital
Outcome results
None listed