Chronic kidney disease (CKD)
Conditions
Interventions
Basic treatment + Zhi Xiong Tong Luo Capsules combined with Ten-Ingredient Kidney Detoxification Solution:In addition to the basic treatment according to Western medical standards, Zhi Xiong Tong Luo
Participating Qi and Nourishing Kidney Granules Combined with Ten-Ingredient Kidney Detoxifying Solution: In addition to the basic treatment based on Western medical standards, the patient is advised
Basic treatment according to Western medicine standards:Western medical basic treatment
Sponsors
Chongqing Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Patients diagnosed with chronic kidney disease. 2) Age = 18 years to = 75 years, both genders. 3) CKD stage 3-5, with renal function eGFR > 15 to = 60 ml/min/1.73m2 (calculated using the CKD-EPI equation), and no need for blood purification treatment. 4) Signed informed consent form.
Exclusion criteria
Exclusion criteria: 1) Abnormal liver function (ALT, AST greater than 2.5 times the upper limit of normal). 2) Patients with a recent history (within three months) of severe cardiovascular diseases such as myocardial infarction, coronary artery bypass grafting, or ischemic heart disease with heart failure (functional class III-IV, NYHA classification). 3) Patients with a recent history (within three months) of severe cerebrovascular diseases such as stroke, or significant neurological functional impairment after stroke. 4) Patients with a recent history (within three months) of active gastrointestinal bleeding. 5) Known severe thrombocytopenia (PLT 5.5mmol/L. 7) History of allergy to the components of the investigational drug. 8) Pregnant or lactating women. 9) Patients scheduled for urgent hemodialysis treatment. 10) Currently using corticosteroids, non-steroidal anti-inflammatory drugs, or immunosuppressive agents. 11) Other diseases or conditions, as determined by the investigator, that may reduce the likelihood of enrollment or complicate the study, such as mental illness, frequent changes in living and working environment leading to loss to follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite Endpoints:GFR is not decreased, with an increase of less than 10%; blood creatinine is not increased, or decreased by less than 10%; all-cause mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in traditional Chinese medicine syndrome efficacy score;Kidney function; | — |
Countries
China
Contacts
Public ContactXiong Weijian
Chongqing Traditional Chinese Medicine Hospital
Outcome results
None listed