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Evaluation of the effectiveness of Coix lacrymae and different concoctions in people with eczema caused by spleen deficiency and dampness

Evaluation of the effectiveness of Coix lacryma and different concoctions in people with eczema with spleen deficiency and dampness - a prospective, double-blind, randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2023000048
Enrollment
Unknown
Registered
2023-09-25
Start date
2023-10-07
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spleen deficiency and dampness type eczema

Interventions

4:Control group: rice (rice granules), orally, 30g/dose, 1 time/day
3:Test group 3: Fagopyrum (Fagopyrum granules), taken orally, 30 g/dose, 1 time/day
2:Test group 2: bran fried coix seeds (bran fried coix granules), taken orally, 30 g/time, 1 time/day
1:Test group 1: raw Coix seeds (Coix seeds made into granules), taken orally, 30 g/dose, 1 time/day

Sponsors

Affiliated Hospital of Jiangxi University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1) Age 18 to 65 years old, regardless of gender; 2) Those diagnosed with eczema of the spleen deficiency and dampness type; 3) Those who have not participated in other clinical studies within 3 months; 4) Those who voluntarily participated in this project with follow-up after adequate communication and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1) combined with serious primary diseases of the heart, brain and hematopoietic system, combined with serious liver and kidney function impairment, with malignant tumors, etc; 2) in the preparation period, pregnancy or breastfeeding period (3) Combined with a major mental illness and unable or unwilling to cooperate 4) Known hypersensitivity to the components of this test article; 5) Those who have used Chinese medicine or proprietary Chinese medicine with similar efficacy to Coix Seed and different concoctions in the last 2 weeks, which affects the judgment of the results.

Design outcomes

Primary

MeasureTime frame
ATP;Eczema Area and Severity of Involvement Scale (EASI) scale;AQP3;Pruritus level (VAS) scale;Chinese Medicine Evidence Scale;phospho-p38 MAPK,p38MAPK;—

Secondary

MeasureTime frame
Trans Epidermal Water Loss, TEWL;Skin Barrier Test;Dermatology Quality of Life Index (DLQI) Scale;Skin surface pH;eosinophil;neutrophil;stratum corneum hydration,SCH;Sebum content;—

Countries

China

Contacts

Public ContactYi xingqian;Chen Xiaofan

The Affiliated Hospital of Jiangxi University of Chinese Medicine; Jiangxi University of Chinese Medicine;

xiaofanci122306@163.com118770010316;8507915566;

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026