Acute pharyngitis
Conditions
Interventions
placebo group:Lianhua Qingwen Granule Simulator
test group:Lianhua Qingwen Granules
Sponsors
The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Conforming to the diagnosis of acute pharyngitis in Western medicine; 2) Age range from 18 to 65 years old (including boundary values at both ends), regardless of gender; 3) Before enrollment, the researcher evaluated the pharyngeal pain VAS score to be = 4; 4) Patients with a course of disease = 48 hours (defined here as patients who experience symptoms and signs of acute pharyngitis such as sore throat and swollen throat within 48 hours of this visit); 5) Volunteer to participate in clinical trials and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1) Those with an armpit temperature greater than 38.5 ?; 2) White blood cell count>12 × 109/L; 3) Individuals with diarrhea (loose stools) during enrollment; 4) Patients with bronchitis, pneumonia, suppurative Tonsillitis, or pharyngeal symptoms or inflammation caused by measles, Scarlet fever, influenza, agranulocytosis, infectious Monocyte, leukemia, acute carotid arteritis, etc; 5) Liver function ALT and AST exceed the upper limit of the reference value by 1.5 times, or Scr exceeds the upper limit of the reference value; 6) Patients with serious primary diseases or psychosis such as cardiovascular, cerebrovascular, liver, kidney, hematopoietic system, Endocrine system; 7) Allergic constitution (those who are allergic to Class 2 or more substances), as well as those who are allergic to known ingredients or any excipients of the study drug (including placebo); 8) Pregnant or planned pregnancies, or those who cannot strictly control contraception during the trial period, lactating women; 9) Suspected or with a history of alcohol or drug abuse; 10) Individuals who have participated in other clinical trials within a month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Median time of disappearance of pharyngeal pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change rate of total symptom score from baseline on days 3 and 6;Change rate of pharyngeal pain score from baseline on days 3 and 6;Difference in the disappearance time of pharyngeal pain between two groups;The disappearance rate of pharyngeal pain on the 3rd and 6th days; | — |
Countries
China
Contacts
Public ContactYan Ruan
The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
Outcome results
None listed