Sepsis
Conditions
Interventions
Supplemented Xijiao Dihuang Tang combined with conventional Western medicine treatment group:Oral or nasal feeding Supplemented Xijiao Dihuang Tang combined with conventional Western medicine treatme
(2) Use dynamic monitoring to guide fluid resuscitation, such as stroke volume (SV), stroke volume variation (SVV), pulse pressure variation (PPV), and echocardiography
(3) The use of antibiotics: for suspected septic shock or sepsis patients, anti-infection therapy should be carried out immediately within 1 hour of definite diagnosis
(4) Use of vasoactive agents: norepinephrine is the first choice for patients with septic shock. The mean arterial pressure (MAP) level after norepinephrine was still not up to the standard, and vasop
Sponsors
Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1) Meet the Berlin criteria for Sepsis 3.0; 2) Traditional Chinese Medicine clinical syndrome differentiation was syndrome of heat entering nutrient-blood aspects, and the syndrome type was determined by 2 intermediate professional titles or above; 3) Age =18 years old, gender unlimited; 4) Good compliance, follow-up, voluntary participation in the study, and informed consent signed by oneself or their family members.
Exclusion criteria
Exclusion criteria: 1) Those who do not meet the inclusion criteria; 2) Under the age of 18; 3) lactating and pregnant women; 4) Complicated with serious primary diseases of heart, brain, liver and kidney; 5) Allergic constitution or allergic to the drugs in this study; 6) Mental or cognitive impairment, poor compliance, unable to cooperate with the researcher; 7) Participating in other clinical studies at the same time may affect the observers of effect indicators of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Length of stay in intensive care unit;metabolome(blood);28-day mortality rate;Traditional Chinese Medicine clinical symptom score; | — |
Secondary
| Measure | Time frame |
|---|---|
| hemoglobin;Acute Physiology and Chronic Health Evaluation ? score;Hypersensitive C-reactive protein;Sequential Organ Failure Assessment score;White blood cell count;Modified Marshall score;Platelet count; | — |
Countries
China
Contacts
Public ContactZhijun Fang
Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine
Outcome results
None listed