acute gouty arthritis
Conditions
Interventions
Control group:Loxoprofen Sodium Tablets 60mg + Tongfeng Fang granule simulant
Test group:Tongfeng Fang granule + Loxoprofen sodium analogue tablet 60mg
Sponsors
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: ?Those who meet the diagnostic criteria of primary acute gouty arthritis and the syndrome differentiation criteria of TCM "damp-heat syndrome". ? Male and female patients aged 18-70 years. ?Acute onset, the course of the attack within 48 hours. ?No relevant therapeutic drugs have been taken since the onset of the disease. ?Informed consent, voluntary subjects.
Exclusion criteria
Exclusion criteria: ?Secondary gout, such as renal failure, tumor chemotherapy and/or radiotherapy; ?Patients who were allergic to the drug in this study; ?Have serious heart, liver, lung, hematopoietic system or affect their survival of serious diseases, such as tumor, AIDS; ALT or AST > 2N (N is the upper limit of normal); SCr=132mmol/L (1.5 mg/dl); Arrhythmia of clinical significance; white blood cell<3.0 times 10^9/L; ?Joint lesions caused by rheumatoid arthritis, pyogenic arthritis, traumatic arthritis, psoriatic arthritis, pseudogout, lupus erythematosus and other diseases; ?Hyperuricemia and gout caused by diuretics, compound antihypertensive drugs containing diuretics, ethambutol, pyrazinamide, aspirin and other drugs; ?Hyperuricemia and gout caused by diuretics, compound antihypertensive drugs containing diuretics, ethambutol, pyrazinamide, aspirin and other drugs; ?Pregnant and lactating women; ?Suspected or indeed a history of alcohol or drug abuse, or according to the judgment of the researchers, with the possibility of reducing or complicating the inclusion of other lesions, such as frequent changes in the working environment and other easy to cause the loss of follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analog scale test; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood uric acid;TCM syndrome score;C-reactive protein;Time to onset of pain relief; | — |
Countries
China
Contacts
Public ContactMa Fang
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Outcome results
None listed