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Based on resting state fMRI to explore the therapeutic effect of acupressure stimulation of ST-36-Zusanli in improving the symptoms of chronic superficial gastritis and the central-humoral-metabolic mechanism

Based on resting state fMRI to explore the therapeutic effect of acupressure stimulation of ST-36-Zusanli in improving the symptoms of chronic superficial gastritis and the central-humoral-metabolic mechanism

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2022000077
Enrollment
Unknown
Registered
2022-06-30
Start date
2022-08-12
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

superficial gastritis

Interventions

control group:Acupressure stimulation of sham point.The point about 1.5cm below the midpoint of the connecting line between bilateral Zusanli and Yanglingquan is taken as the sham point.
experimental group:Acupressure stimulation of ST-36-Zusanli

Sponsors

Radiology department of Guang'anmen Hospital of Chinese Academy of traditional Chinese medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Participants with clinical diagnosis of chronic superficial gastritis; (2) Participants from 18 to 75 years of age. No gender limitation. (3) Participants who have voluntarily agreed to participate in the study and have signed written informed consent, and can cooperate with and complete the treatment and follow-up course.

Exclusion criteria

Exclusion criteria: (1) Patients with peptic ulcer, erosive gastritis, atrophic gastritis, severe dysplasia of gastric mucosa or suspected malignant change according to pathological diagnosis; (2) Pathological changes of digestive system, such as liver, gall bladder and pancreas; (3) Chronic superficial gastritis caused by HP infection; (4) Severe liver and kidney dysfunction, serious cardiovascular and cerebrovascular diseases, and malignant tumors; (5) Those who have received anti-inflammatory, anti-acid drugs within 3 months. (6) Pregnant or lactating women: (7) There are pacemakers, defibrillators and other metal products in the body, and people with claustrophobia are not suitable for MRI examination. (8) There were visible structural abnormalities in routine head MRI.

Design outcomes

Primary

MeasureTime frame
fMRI;Symptom score;—

Secondary

MeasureTime frame
index of gastric mucosa repairment;stimulus intensity;Serum levels of inflammatory factors and gastrointestinal hormones;Intestinal microbiota;—

Countries

China

Contacts

Public Contactshifengxiang

Guang'anmen Hospital of Chinese Academy of traditional Chinese medicine

shifengxiang5999@163.com18500305582

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026