Ventilator-Associated Diaphragmatic Dysfunction
Conditions
Interventions
2:fake electroacupuncture
Sponsors
Guang'anmen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Only those who meet all of the following conditions can be included: ? Voluntary participation, understanding and signing the informed consent form; ? Invasive ventilator treatment meets the above diagnostic criteria; ? Age 18-90 years old; gender is not limited; ? No acupuncture or electroacupuncture Contraindications.
Exclusion criteria
Exclusion criteria: Those who meet any of the following conditions should be excluded: ? Factors affecting ultrasound determination: thoracic drainage, abdominal infection, abdominal hypertension, abdominal surgery within the past month, age > 90 or < 18, pregnancy, use within 24 hours Neuromuscular blockers, sedatives, known diaphragmatic deformity or injury; ?Severe metabolic abnormalities, known neuromuscular disease and respiratory center disease; ?Installation of cardiac pacemaker; ?Local lesions such as skin lesions, tumors, etc. 5. Within the 7-day intervention period, acute exacerbation of disease: sepsis, coagulation dysfunction, and multiple organ failure due to acute exacerbation of infection; ? Acute organ dysfunction due to various reasons: liver failure: transaminase within 1 day Increased by more than 100IU/L, or by more than 250IU/L for 3 consecutive days; Renal failure: creatinine increased by more than 70umol/L within 1 day, or increased by more than 170umol/L for 3 consecutive days; Heart failure: BNP increased by 1500pg/ml within 1 day above, or increased by 3000pg/ml or more for 3 consecutive days; pulmonary embolism: new pulmonary embolism with a definite diagnosis; acute pancreatitis: new acute pancreatitis with a definite diagnosis; other new acute diseases that seriously affect the prognosis (such as cerebral infarction) , cerebral hemorrhage, myocardial infarction, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragm thickness variation rate (DTF);Diaphragmatic respiratory activity (DE); | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory factor indicators: TNF-a, IL-1ß, IL-2R, IL-6, IL-8, IL-10;length of hospital stay, cost of hospital stay, time off-line, 28-day mortality;Arterial blood gas indicators (PH, PaO2, PaCO2), oxygenation index (oxygen partial pressure/inhaled oxygen concentration);;Oxidative stress indicators: MDA, SOD;;Ventilator parameters;Ventilator mode; | — |
Countries
China
Contacts
Public ContactYang Jinliang
Outcome results
None listed