metabolic associated fatty liver disease
Conditions
Interventions
one:Tiaoganhuazhuo Decoction Combined with Exercise Therapy
two:Tiaoganhuazhuo Decoction
Sponsors
Guang'anmen Hospital,CHINA ACADEMY OF CHINESE MEDICAL SCIENCE
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ? Conform to MAFLD's western medicine diagnostic criteria and TCM syndrome diagnostic criteria; ? Aged between 18 and 65; ? Those who have good compliance, are willing to cooperate with the treatment, and sign the informed consent form.
Exclusion criteria
Exclusion criteria: ? Pregnant or lactating women; ? Complicated with serious diseases of important organs (such as heart, brain, lung and kidney); ? Patients with infectious hepatitis and liver cirrhosis and liver cancer diagnosed by liver biopsy; Or drug-induced liver disease, genetic factors and other specific diseases that can lead to fatty liver; ? Patients with mental and legal disabilities; ? Suspected or actual history of drug abuse; Alcohol consumption history > 5 years, equivalent to alcohol consumption = 40 g /d for men and = 20 g /d for women; Or have a history of heavy drinking within 2 weeks, equivalent to alcohol volume > 80 g /d; ? Those who are known to be allergic to the components of the drug; ? MRI and exercise contraindications; ? Patients who are participating in other drug clinical trials or who have participated in drug clinical trials within the past month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRI-PDFF; | — |
Secondary
| Measure | Time frame |
|---|---|
| Liver function test;the waist;glycosylated hemoglobin;Hypersensitive C-reactive protein;TCM symptom score;Blood lipid test;uric acid;routine blood test;Fasting blood glucose;Body mass index; | — |
Countries
People's Republic of China
Contacts
Public ContactXiaping Tao
Outcome results
None listed