Diabetic kidney disease
Conditions
Interventions
Experimental group:Qihuang Yishen Granules
control group:Qihuang Yishen Granules Mimic
Sponsors
Wangjing Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria for diabetic kidney disease; (2) Age 30 to 85 years old; (3) Blood pressure = 150/90mmHg; (4) Glycosylated hemoglobin = 8.5%; (5) eGFR=25ml/min (6) Sign the informed consent form and follow up on time.
Exclusion criteria
Exclusion criteria: (1) Blood pressure < 90/60mmHg; (2) Blood creatinine doubled in the past six months; (3) Unilateral or bilateral renal artery stenosis; (4) Serious large vascular events have occurred in the past six months; (5) Complicated by malignant tumors, hematologic diseases and other serious diseases; (6) There is a serious psychological or mental abnormality; (7) Pregnant or lactating women; (8) Considering other renal diseases complicated by other kidney diseases (such as urinary tract infections, urinary sediment activity manifestations (red blood cells), etc.) that require renal puncture to confirm the diagnosis; (9) Those who have undergone dialysis or kidney transplantation. Note: Any of the above conditions will not be included.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour urine protein quantification; | — |
Secondary
| Measure | Time frame |
|---|---|
| urea nitrogen;Estimated glomerular filtration rate;Urine microalbumin to creatinine ratio;Serum creatinine;TCM symptom score;metabolomics;Gut flora; | — |
Countries
China
Contacts
Public ContactLiu Shiwei
Outcome results
None listed