Clinical study of CCTA-FFRCT combined evaluation of coronary ischemia in early stage of coronary heart disease with traditional Chinese medicine

Scientific and technological innovation project of China Academy of Chinese Medical Sciences

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ITMCTR

Registry ID

ITMCTR2022000025

Enrollment

Unknown

Registered

2022-06-17

Start date

2022-07-01

Completion date

Unknown

Last updated

2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stable Angina Pectoris of Coronary Heart Disease

Interventions

The test group:Chinese medicine and western medicine standard treatment

The control group:Western standard treatment for coronary heart disease

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: (1) It meets the diagnostic criteria of stable angina pectoris of coronary heart disease in Western medicine, and CTA shows that at least one major branch has a lumen diameter narrowing of 50%-75%; (2) 0.7 < FFRCT=0.8; (3) Meet the standard of TCM syndrome differentiation of chest obstruction and blood stasis; (4) Aged 18-85, with no gender limitation; (5) those who have not taken other Chinese herbs in the last two weeks; (6) Those who voluntarily participate and sign the informed consent of patients.

Exclusion criteria

Exclusion criteria: (1) Patients with a history of acute myocardial infarction in the last 3 months; (2) Patients with a history of serious arrhythmias, such as ventricular fibrillation, degree III ATrioventricular block, etc.; (3) Poor blood pressure control (systolic blood pressure =180mmHg or diastolic blood pressure =120mmHg); (4) serious diseases of liver, kidney, respiratory system, blood system, endocrine system and malignant tumors; (5) Women who are currently preparing for pregnancy, pregnancy or breastfeeding; (6) severe cardiac neurosis, perimenopausal syndrome, etc.; (7) patients suffering from mental disorders, or serious alcoholism and other adverse intoxication; (8) allergic to Chinese herbal medicine; (9) Incomplete medical records; (10) The researchers assessed other conditions for exclusion. Those who meet any of the above criteria will not be included in the test.

Design outcomes

Primary

Measure	Time frame
Noninvasive Fractional Flow Reserve Derived from Coronary CT;	—

Secondary

Measure	Time frame
TCM syndrome integral;Ultrasonic diastolic function parameter -- E/ e';	—

Countries

China

Contacts

Public ContactWu Huaqin

yuanshanyun2650@163.com13466679735

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026