bacterial infection
Conditions
Interventions
control group:Ceftazidime for Injection
Trial group:Ceftazidime for Injection + Tanreqing Injection
Sponsors
Medical Experimental Center of China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: ? Meet the diagnostic criteria of lower respiratory tract infection (pneumonia, acute exacerbation of chronic obstructive pulmonary disease, bronchiectasis complicated infection) and need antibiotic treatment; ?Age between 40 and 80 years old (including 40 and 80 years old); ? Obtain qualified sputum specimens of the lower respiratory tract (sputum smear: =10 squamous epithelial cells in each low-power microscope field, and =25 leukocytes per low-power field), and the sputum bacteria were cultured as drug-resistant Pseudomonas aeruginosa bacteria; ? In line with the syndrome of phlegm-heat obstructing the lung; ? Accept the treatment plan voluntarily and sign the informed consent.
Exclusion criteria
Exclusion criteria: ? Pulmonary tuberculosis patients; ? Non-resistant Pseudomonas aeruginosa infection; ? Immunodeficiency patients or taking immunosuppressive agents or glucocorticoids within the past 3 months; ? Patients with severe liver and kidney dysfunction, severe pulmonary heart disease with heart failure or hematopoietic system and other serious primary diseases; ? Pregnant and lactating patients; ? Those who are allergic to the study drug or its components; ? Other doctors think that it is not suitable to participate in this researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Drug allergy testing; | — |
Secondary
| Measure | Time frame |
|---|---|
| 16S rDNA, metagenomic sequencing; | — |
Countries
China
Contacts
Public ContactWang Yi
Medical Experimental Center of China Academy of Chinese Medical Sciences
Outcome results
None listed