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Basic research for sepsis with gastrointestinal dysfunction by internal and external treatment therapy

Basic research for sepsis with gastrointestinal dysfunction by internal and external treatment therapy

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2022000015
Enrollment
Unknown
Registered
2022-06-17
Start date
2022-07-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Sponsors

Xiyuan Hospital, Chinese Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. ICU/EICU stay for more than 7 days; 2. Age 18-85 years old; 3. Those who meet the diagnostic criteria for sepsis; 4. Those who meet the diagnostic criteria for gastrointestinal dysfunction; 5. Those who meet the gastrointestinal dysfunction score = 1; 6. Those who meet the APACHE II score = 15 points; 7. Those who voluntarily or family members agree and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Those who do not have the conditions for enteral feeding; 2. Those who have gastrointestinal dysfunction caused by primary gastrointestinal diseases or trauma; 3. Those who are diagnosed with gastrointestinal malignant tumors or other advanced malignant tumors; 4. Those who do not have bladder Those with pressure measurement conditions (bladder injury or contracture, urethral stenosis or rupture, etc.); 5. Those who used glycerin enema, mosapride, lactulose and other drugs to improve gastrointestinal function within 1 week before the test; 6. Those suffering from mental disorders; 7. Those who are pregnant or breastfeeding; 8. Those who are participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
APACHE II score;TCM symptom score;serum lymphokine;Gastrointestinal Dysfunction Score;Intestinal fatty aid binding protein;intra-abdominal pressure;Peripheral blood T lymphocyte subsets;

Countries

China

Contacts

Public Contacthuangye

Xiyuan Hospital of China Academy of Chinese Medical Sciences

yellow_926@163.com15011367940

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026