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Clinical efficacy of Wendanningxin granule in the treatment of mild to moderate anxiety

Clinical efficacy of Wendanningxin granule in the treatment of mild to moderate anxiety

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2022000012
Enrollment
Unknown
Registered
2022-06-14
Start date
2022-08-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

moderate anxiety

Interventions

control group:Citalopram Hydrobromide Tablets
treatment group:Wendanningxin granule

Sponsors

Guang'anmen Hospital, Chian Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Age: 18 ~ 65 years old, both male and female; (2) Conform to the diagnostic criteria of anxiety disorder in western medicine and the diagnostic criteria of heart and gall Qi deficiency syndrome; (3) At the time of enrollment, the total score of HAMA Anxiety Scale (17 items) was = 14 and = 29; (4) The total score of HAMD depression scale = 7 at the time of enrollment; (5) Informed consent and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Those with suicidal tendencies; (2) Severe anxiety (HAMA total score >29); (3) Anxiety attack secondary to other mental or physical diseases and accompanied by severe psychotic symptoms; (4) Patients with severe diseases of other systems and severe heart, liver and kidney dysfunction (including ALT and AST 1.5 times higher than normal); (5) Those who had taken anti anxiety agents within four weeks before enrollment; (6) Pregnancy or lactation or pregnancy; Women of childbearing age with positive urine pregnancy test; (7) Known alcoholics or drug addicts.

Design outcomes

Primary

MeasureTime frame
Hamilton Anxiety Scale;Self rating Anxiety Scale;Near infrared quantitative brain function imaging;

Secondary

MeasureTime frame
Hamilton Depression Scale;Pittsburgh sleep quality index;

Countries

China

Contacts

Public ContactYAN XUE

Guang'anmen Hospital, Chian Academy of Chinese Medical Sciences

yanxdoc@163.com13466765819

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026