Radiation proctitis
Conditions
Interventions
control group:Nil
Sponsors
Guangdong Provincial Hospital of Traditional Chinese Medicine (the Second Affiliated Hospital of Guangzhou University of traditional Chinese Medicine)
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients who have received radical radiotherapy or hysterectomy plus adjuvant radiotherapy after pathological diagnosis of cervical cancer; 2. Patients with local recurrence of cervical cancer 3 months after the end of treatment were confirmed by pathology and imaging; 3. Patients who received external pelvic radiation therapy (EBRT) and intracavitary brachytherapy (BT) were treated with radiotherapy; 4. Patients with chronic radiation proctitis before radiotherapy and the severity should be less than or equal to grade I. 5. Patients with KPS score >= 60; 6. Patients who voluntarily participated in the trial and signed informed consent in writing; 7. Patients aged 18-75 years.
Exclusion criteria
Exclusion criteria: 1. Patients with other malignant tumors before enrollment; 2. Those patients whose first treatment after diagnosis of cervical cancer does not include radiotherapy; 3. Patients with distant recurrence at the same time; 4. Patients with serious organic diseases such as heart, lung, liver and kidney; 5. Patients with severe radiation proctitis (acute grade >= 3 or chronic grade = III) in the first radiotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The whole rectal wall volume of radiation dose;The rate of acute radiation proctitis;The posterior rectal wall volume of radiation dose;High dose equivalent biological dose to the rectal wall (EQD2);The anterior rectal wall volume of radiation dose; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of severe acute radiation proctitis (>=Grade 3);Local control rates of recurrent tumors; | — |
Countries
China
Contacts
Public ContactGao Lei
Guangzhou University of traditional Chinese Medicine
Outcome results
None listed