Control Body Tumor Microenvironment by Amelioration of Chronic Stress with Chinese Medicine of of Sanhuang Decoction (SHD) During Endocrine Treatment in Breast Cancer Patients

Clinical trial on reducing oxidative stress and inflammatory responsewith San Huang Decoction on the breast cancer patients during perioperative period

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ITMCTR

Registry ID

ITMCTR2000004194

Enrollment

Unknown

Registered

2020-12-25

Start date

2017-04-20

Completion date

Unknown

Last updated

2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

Experimental group:The SHD decoction + basic treatment

Control group:Basic treatment

Eligibility

Sex/Gender

Female

Age

30 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. All patients must be diagnosed with breast cancer, 2. Patients who plan to undergo planned modified radical surgery between 30 and 70 years old.

Exclusion criteria

Exclusion criteria: 1. Patients with history of other malignant tumors; 2. Patients who use steroids to inhibit inflammatory reaction; 3. Patients with poor cooperation; 4. Patients with previous psychiatric history; 5. subjects who are participating in other drug clinical trials.

Design outcomes

Primary

Measure	Time frame
TNF-a;CD8;HDL-C;LDL-C;TG;GSH-px;TAOC;NO;CA153;IgA;IgG;C3;C4;IL-8;CD3;apo-B;apo-A;SOD;VEGF;TC;IgM;CEA;MAD;CA125;CD4;IL-6;	—

Countries

China

Contacts

Public ContactYao Chang

Affiliated Hospital of Nanjing University of Traditional Chinese Medicine

yaochang67@126.com+86 13770549638

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026