perianal chronic eczema
Conditions
Interventions
control group:triamcinolone acetonide and econazole cream
Observation group:External use of fuzhiqing ointment
Sponsors
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) The age ranged from 18 to 65 years old; (2) It was in accordance with the diagnostic criteria of perianal chronic eczema; (3) The subjects voluntarily signed a written informed consent form.
Exclusion criteria
Exclusion criteria: (1) Eczema is found in the area outside the perianal skin; (2) Other active skin diseases (such as psoriasis, acne, syphilis, skin tuberculosis, lupus erythematosus, perioral dermatitis and acne vulgaris) that may affect the evaluation of the results. (3) There are serious diseases of heart, lung, liver, kidney, nerve, endocrine and other systems. (4) The laboratory examined the ALT >=60u/l, and the serum creatinine (CR) was more than 106 umol/l or bun was more than 7.14mmol/l; (5) The infection of bacteria, fungi or virus in the local or drug-use areas of skin lesions needs anti infection treatment; (6) The patients who had been treated with antihistamines within 2 weeks, who had received ultraviolet light therapy within 4 weeks, who had systemic application of aspirin, glucocorticoids or immunosuppressants within 4 weeks; those who used topical drugs in local skin lesions within 1 week, including skin moisturizers; (7) The drug with similar composition and chemical structure is known to have allergy history; the drug has a history of hypersensitivity to food and drug; (8) Participated in other clinical researchers of experimental drugs within 1 month; (9) Alcohol, drug abuse, known drug dependence; (10) Pregnant, prospective or lactating women and staff directly involved in the study; (11) Mental illness patients; (12) The researchers judged that it was not suitable for other cases to participate in clinical research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DLQI;EASI;SF-36;Pruritus score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurrence rate;Skindex16;Patients' self rating eczema severity score;POEM;Effective time;SCORAD index;WHOQOL-BREF;EQ-5D;Insomnia score; | — |
Countries
China
Contacts
Public ContactSUN SONGPENG
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
Outcome results
None listed