post-stroke cognitive impairment no dementia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) From 50 to 85 years old, male or female, receive education above the primary school; (2) Meet the PSCIND diagnostic criteria; (3) Neuroimaging(CT or MRI) supports the diagnosis of cerebrovascular diseases; (4) Patients can move freely by himself or with the aid of a caregiver; (5) Good audio-visual function ensuring cooperation with the examination and treatment; (6) The subjects are voluntary and have signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Diagnosis of Dementia, or cognitive impairment caused by other causes except for stroke; (2) Delirium, depression, or other neurological disorders; (3) Have severe comorbidity such as the severe liver and kidney dysfunction, or severe heart failure, etc.; (4) Use other medications or therapies that may affect cognitive function; (5) Participate in other clinical studies within the last three months; (6) Meet the contraindications of experimental medicines or allergic to experimental medicines.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment, MOCA; | — |
Secondary
| Measure | Time frame |
|---|---|
| Activity of Daily Living, ADL;inflammatory cytokines;Vitamin D;homocysteine;Parathyroid hormone;Mini Mental State Examination Scale (MMSE); | — |
Countries
China
Contacts
Guangdong Provincial Hospital of Chinese Medicine