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Study on the Therapeutic Effect and Mechanism of Yinaokang on Post-stroke Cognitive Impairment No Dementia

Study on the Therapeutic Effect and Mechanism of Yinaokang on Post-stroke Cognitive Impairment No Dementia

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2000004178
Enrollment
Unknown
Registered
2020-09-30
Start date
2020-09-30
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-stroke cognitive impairment no dementia

Interventions

experimental group:Western medicine treatment + Yi-nao-kang capsule

Sponsors

GuangDong Provincial Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) From 50 to 85 years old, male or female, receive education above the primary school; (2) Meet the PSCIND diagnostic criteria; (3) Neuroimaging(CT or MRI) supports the diagnosis of cerebrovascular diseases; (4) Patients can move freely by himself or with the aid of a caregiver; (5) Good audio-visual function ensuring cooperation with the examination and treatment; (6) The subjects are voluntary and have signed informed consent.

Exclusion criteria

Exclusion criteria: (1) Diagnosis of Dementia, or cognitive impairment caused by other causes except for stroke; (2) Delirium, depression, or other neurological disorders; (3) Have severe comorbidity such as the severe liver and kidney dysfunction, or severe heart failure, etc.; (4) Use other medications or therapies that may affect cognitive function; (5) Participate in other clinical studies within the last three months; (6) Meet the contraindications of experimental medicines or allergic to experimental medicines.

Design outcomes

Primary

MeasureTime frame
Montreal Cognitive Assessment, MOCA;

Secondary

MeasureTime frame
Activity of Daily Living, ADL;inflammatory cytokines;Vitamin D;homocysteine;Parathyroid hormone;Mini Mental State Examination Scale (MMSE);

Countries

China

Contacts

Public ContactSun Jingbo

Guangdong Provincial Hospital of Chinese Medicine

gdszyysjb@gzucm.edu.cn+86 13642627661

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026