premature ovarian insufficiency
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Aged 18-40 years; 2) Meet the diagnostic criteria of POI or in the subclinical stage of POI.
Exclusion criteria
Exclusion criteria: 1) Patients with polycystic ovary syndrome, hyperprolactinemia, hyperandrogenism, hypothyroidism, adrenocortical hypofunction and other endocrine diseases that affect ovulation; 2) Patients with severe cardiovascular and cerebrovascular diseases, nephropathy ,hepatopathy, malignant tumor, hematopoietic diseases and mental disease; 3) Patients who refused to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AFC;microRNA; | — |
Secondary
| Measure | Time frame |
|---|---|
| clinical pregnancy;basal serum level of FSH, LH and E2;Numbers of retrieved oocytes;AMH; | — |
Countries
China
Contacts
Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences