Asthenospermia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Meet the western medical diagnostic criteria of "male infertility" and "asthenospermia", and have the two diagnoses at the same time; (2) TCM syndrome differentiation conforms to kidney deficiency syndrome; (3) Male aged 22 to 45 years; (4) Married, husband and wife have a harmonious family relationship; (5) Sperm DNA fragmentation index (DFI) >=30%; (6) No other organic lesions of the reproductive system; (7) Those who did not receive treatment with similar drugs or other therapies within 2 weeks before the study; (8) Understand the content of the study and sign the informed consent. Those who meet the above 8 criteria at the same time will be included in the study; otherwise, they will not be included
Exclusion criteria
Exclusion criteria: (1) According to the Manual of Human Semen Examination and Treatment Laboratory, edition 5, except for total sperm motility < 40% and forward motility < 32%, there are other abnormalities in semen examination; (2) Patients with a family history of genetic diseases; (3) Suffering from varicocele, prostatitis and other diseases that lead to sperm quality decline; (4) Patients with active infection; (5) Patients with severe primary diseases such as cardiovascular, liver, kidney and hematopoietic system; (6) Patients with mental disorders; (7) Patients who have a long-term and large amount of smoking and drinking habits, or are exposed to high temperature, radiation and toxic chemical environment, but cannot change or give up; (8) Allergic constitution and allergic to multiple drugs. Meeting any of the above is considered as meeting the exclusion criteria, and exclusion is required.Those who meet the above 8 criteria at the same time will be included in the study; otherwise, they will not be included
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Semen routine; | — |
Countries
China
Contacts
Dongzhimen Hospital, Beijing University of Chinese Medicine