Decreased ovarian reserve
Conditions
Interventions
control group:Oral placebo
Sponsors
Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: The inclusion criteria of the observation group were as follows: 1. Married female patients aged 20 ~ 40 years old, Those with fertility requirements; 2. Meet the diagnostic criteria for infertility due to decreased ovarian reserve function, and TCM syndrome differentiation belongs to kidney-yang deficiency; 3. No obvious abnormality was found in the sperm examination of the male; 4. Volunteer to participate in this study and sign the informed consent, can actively cooperate with the follow-up, complete the clinical observer. The inclusion criteria of the control group were as follows: 1. Married female patients aged 20 ~ 40 years old, those with fertility requirements; 2. In line with the diagnostic criteria of tubal obstructive infertility; 3. In line with the standard of normal ovarian reserve function; 4. No obvious abnormalities were found in the sperm examination of the man; 5. Voluntarily participate in this study and sign the informed consent, actively cooperate with the follow-up visits and complete the clinical observation.
Exclusion criteria
Exclusion criteria: 1. Those with previous mental illness or allergic constitution; 2. Previous history of various malignant tumors, cardiovascular and cerebrovascular disease, abnormal liver and kidney function, or hematopoietic system and other serious primary diseases; 3. Men with abnormal reproductive functions; 4. Women with polycystic ovary syndrome, immune factors, endometriosis and other infertility factors; 5. Organic lesions or congenital physiological defects or malformations of the reproductive system; 6. Long-term application of exogenous hormone therapy for patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum estradiol;Serum follicle-stimulating hormone;Serum anti-Mullerian hormone;Sinus follicle count;Serum progesterone;Serum luteinizing hormone; | — |
Secondary
| Measure | Time frame |
|---|---|
| Grade III oocyte rate;High quality embryo rate;Syndrome integral of kidney-Yang deficiency;Fertilization rate;The oocyte count was obtained; | — |
Countries
China
Contacts
Public ContactXiaole Zhang
Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed