Small Airway Disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. More than 18 years old, male or female; 2. Meet the pulmmonary function criteria for small airway disease: MMEF, FEF50, FEF75 decreased, and more than 2 indicators were lower than 65% of the expected value; 3. Willing to take oral Chinese medicine treatment; 4. Able to communicate and write in language or text; 5. Sign the informed consent form voluntarily.
Exclusion criteria
Exclusion criteria: 1. There are major diseases, such as lung malignant tumors, heart failure, renal failure, dementia, epilepsy, active tuberculosis, etc.; 2. Using respiratory drugs in past weeks,such as inhaled corticosteroids, anticholinergic drugs, ß2 receptor agonists, leukotriene receptor antagonists, etc.; 3. Currently in acute exacerbation of respiratory diseases, such as acute exacerbation of chronic obstructive pulmonary disease, acute exacerbation of asthma, etc.; 4. Acute cardiovascular and cerebrovascular events (stroke, transient ischemic attack, acute coronary syndrome) in the past 3 months; 5. History of malignant tumors that are not completely cured; 6. Mental illness, drug addiction or alcoholism; 7. Lactation, pregnancy, or planned pregnancy in the near future; 8. History of allergy to Chinese medicinal materials, or unwillingness to take Chinese medicinal preparations; 9. Those who are not expected to cooperate or are not suitable for follow-up; 10. The informed consent is not signed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary Function Test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammation Biomarkers;Induced Sputum;Respiratory Questionnaire; | — |
Countries
China
Contacts
SHANTOU CENTRAL HOSPITAL