IgA nephropathy
Conditions
Interventions
Sponsors
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The diagnosis was IgA nephropathy, and the pathologic reports of renal perforation were reported in all cases; 2. No gender limitation, aged 18-70 years; 3. Moderate proteinuria(24-hour urinary protein quantity is between 1.0-2.5g)accompanied or not accompanied by microscopic hematuria; 4. CKD1-2 (GFR>=60ml/min/1.73m2); 5. TCM syndrome differentiation accords with qi deficiency and blood stasis syndrome as well as wind pathogen and heat toxicity; 6. Non-dialysis patients with infection, acidosis, electrolyte disturbance, hypertension and other aggravating factors are effectively controlled and the condition is stable. The BP is between 130-90/80-60mmHg. Potassium is in the normal range; 7. Voluntarily accept this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Secondary factors leading to proteinuria, such as purpura nephritis, lupus nephritis; 2. Patients who have been treated by glucocorticoid, immunosuppressant, tripterygium wilfordii preparation in three months are not included; 3. Having mental illness, infectious disease or lactation, pregnancy or planned pregnancy during the study period; 4. Patients complicated with serious diseases of the heart, brain, liver and hematopoietic system, or other serious diseases affecting their survival; 5. Patients with unilateral or bilateral renal artery stenosis; 6. Participants who are participating in other interventional clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urine protein quantitation for 24 hours; | — |
Secondary
| Measure | Time frame |
|---|---|
| Routine urine;TCM symptom score;Blood fat;renal function; | — |
Countries
China
Contacts
Public ContactZhang Yu
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed