Endometriosis
Conditions
Interventions
Healthy control group:Nil
Sponsors
Dongfang Hospital of Beijing University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for dysmenorrhea patients with endometriosis: 1. Patients with EM diagnosis; 2. Patients with dysmenorrhea symptom score >= 7.5 according to the guiding principles for clinical research of new drugs of traditional Chinese medicine (1993); 3. Patients with kidney deficiency and blood stasis syndrome in TCM; 4. Patients with age >= 20 and = 20 and <= 45 years; 2. After physical examination, the subjects whose physiological indexes were in the normal range had no previous functional or organic diseases, no head injury and no dysmenorrhea symptoms; 3. Right handedness subjects were assessed by oldfriedls Edinburgh Handedness scale; 4. For those subjects without metal implants in vivo, there was no MRI contraindication; 5. Subjects who voluntarily signed informed consent. Healthy people meeting all the above inclusion criteria will be considered for inclusion.
Exclusion criteria
Exclusion criteria: Exclusion criteria for dysmenorrhea patients with endometriosis 1. Patients with ovarian malignant tumor, pelvic inflammatory mass, adenomyosis, hysteromyoma > 4cm, primary dysmenorrhea, or women with IUD; 2. Patients who have used drugs or other therapies for endometriosis in recent 3 months (including laparoscopy); 3. Patients with ovarian chocolate cyst diameter > 5cm; 4. Patients with hemoglobin the upper limit of normal value, kidney disease; patients with bun and SCR > the upper limit of normal value, diabetes mellitus; 6. Patients with allergic constitution or allergic to the test drug; 7. Patients who should pay attention to ibuprofen sustained release capsules include gastrointestinal diseases, renal insufficiency, hypertension, cardiac insufficiency, peptic ulcer, hemophilia or other hemorrhagic diseases (including coagulation or platelet dysfunction) and bronchial asthma; 8. Patients who took painkillers, sedatives, tea and coffee within 24 hours before MRI examination and had nausea and vomiting before MRI examination; 9. Pregnant or lactating women who have fertility requirements in the past six months; 10. Patients considered unsuitable by doctors to participate in clinical trials. All patients with EM dysmenorrhea in accordance with any of the above items were excluded. Exclusion criteria for healthy subjects: 1. Pregnant or lactating women who have fertility requirements in the past six months; 2. Subjects who have taken excitatory drugs in the past 3 months; 3. Subjects who have received traditional Chinese medicine treatment in the past three months; 4. Subjects who are participating in other clinical trials. Those who meet any of the above criteria are excluded.
Countries
China
Contacts
Public ContactGong Xin
Dongfang Hospital of Beijing University of traditional Chinese Medicine
Outcome results
None listed