Parkinson's disease
Conditions
Interventions
Acupuncture group:Acupuncture treatment
Sponsors
Linyi People's Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. In line with the diagnostic criteria of Western medicine for Parkinson's disease; 2. Meet the diagnostic criteria of Roman IV diagnostic criteria for functional constipation; 3. Aged between 40 to 80 years old; 4. Hoehn & Yahr grade < 3; 5. Informed consent and willing to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Patients with constipation due to serious gastrointestinal and digestive diseases; 2. Patients with severe mental illness or cognitive impairment (Mini-mental State Examination(MMSE): the illiterate; educational level is < 17 scores, the primary school educational level is < 20 scores, and the secondary school and above educational level is< 24 scores); 3. Patients with serious cardiovascular and cerebrovascular diseases, hematopoietic diseases, malignant tumors and other serious life-threatening diseases; 4. Patients who used probiotics or antibiotics within 1 month before sample collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composition of gut microbiota;spontaneous bowel movements (SBMs) per week; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bristol;CCS;UPDRS-III;PDQ-39;HAMD;HAMA; | — |
Countries
China
Contacts
Public ContactFengyuan Che
Linyi People's Hospital
Outcome results
None listed