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Efficacy and Safety of Chinese Medicine Nanbei Decoction Combined With Androgen Blockade in The Treatment of Advanced Prostate Cancer: a Randomized, Double-Blind, Placebo-Controlled Clinical Study

Efficacy and Safety of Chinese Medicine Nanbei Decoction Combined With Androgen Blockade in The Treatment of Advanced Prostate Cancer: a Randomized, Double-Blind, Placebo-Controlled Clinical Study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2000004034
Enrollment
Unknown
Registered
2020-08-29
Start date
2020-10-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Advanced Prostate Cancer

Interventions

Sponsors

Department of Urology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) It is in accordance with the diagnostic standard of Western medicine for "advanced prostate cancer". (2) It is in accordance with the TCM diagnostic standard of Qi and yin deficiency syndrome. (3) In the stage of maximal androgen blockade treatment; (4) Sign informed consent.

Exclusion criteria

Exclusion criteria: (1) Hepatitis A, hepatitis B, hepatitis C and other infectious diseases; (2) Abdominal ultrasound showed obstructive disease, abdominal CT showed liver metastasis; (3) Liver function is not complete; (4) Severe cardiovascular and cerebrovascular diseases, renal insufficiency and mental history; (5) Primary malignant tumor, except prostate cancer. (6) In recent 3 months, he has taken other drugs (including traditional Chinese Medicine) in addition to anti male treatment.

Design outcomes

Primary

MeasureTime frame
Quality of life FACT-P score;PSA response time;Evaluation of tumor focus;

Secondary

MeasureTime frame
TCM syndrome score;Incidence of anti male reaction;Incidence of castration resistance;

Countries

China

Contacts

Public ContactWen-Jing Zhu

Department of Urology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine

zwjmnk@163.com+86 18121202509

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026